Fig. 2 | International Journal of Oral Science

Fig. 2

From: Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastoma

Fig. 2

Single-cell transcriptomic analysis identifies intratumoral heterogeneity and diversity in ameloblastoma. a UMAP plot classifying 26,956 epithelial cells into five clusters with immune response (IR), bone remodeling (BR), tooth development (TD), epithelial development (ED), and cell cycle (CC). b UMAP plot displaying the expression of selected marker genes in different epithelial cell types. c Heatmap showing the differently expressed genes of each cluster, representative marker genes in the right panel. d Representative images of multiplex immunohistochemistry showing the expression of PCK, HLA-B, KRT13 (CK13), SFRP1, ODAM, LAMC2, and KI67 in ameloblastoma; scale bar, 50 μm

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