Fig. 3 | International Journal of Oral Science

Fig. 3

From: Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastoma

Fig. 3

The CC subpopulation is correlated with recurrence in ameloblastoma. a UMAP plot showing all epithelial cells that were divided into primary and recurrent samples. b Bar plot showing the relative percent of different tumor cell subpopulations in primary and recurrent samples. c UMAP plot showing the expression of MKI67, TOP2A, CCNB2, CCNB1, CDK1, and CENPF in epithelial cells derived from primary and recurrent samples. d Representative images of KI67 IHC staining in primary and recurrent ameloblastoma, scale bar 100 μm (left panel). Quantification of KI67 expression in primary and recurrent ameloblastoma (right panel). ***P < 0.001 by Student’s t test. e Representative images of KI67 IHC staining in unicystic and conventional ameloblastoma; scale bar, 100 μm (left panel). Quantification of KI67 expression in unicystic and conventional ameloblastoma (right panel), ***P < 0.001 by Student’s t test

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