Fig. 8

EZH2 expression is increased in recurrent AM and positively correlated with KI67 expression. a Violin plot showing the expression of EZH2 in the five clusters after splitting epithelial cells into primary and recurrent groups. b Representative images of EZH2 IHC staining in primary and recurrent ameloblastoma; scale bar, 100 μm (left panel). Quantification of EZH2 IHC staining in primary and recurrent ameloblastoma, ***P < 0.001 by Student’s t test (right panel). c Representative images of EZH2 IHC staining in unicystic and conventional ameloblastoma; scale bar, 100 μm (left panel). Quantification of EZH2 IHC staining in unicystic and conventional ameloblastoma, ***P < 0.001 by Student’s t test (right panel). d Representative images showing the same region of KI67 and EZH2 IHC staining in serial sections; scale bar, 100 μm (left panel). The correlation analysis between the expression of KI67 and EZH2 was assessed, ***P < 0.001 by Pearson (right panel)