Fig. 4 | International Journal of Oral Science

Fig. 4

From: Periodontitis exacerbates pulmonary hypertension by promoting IFNγ+ T cell infiltration in mice

Fig. 4

P. zoogleoformans promotes the accumulation of IFNγ+ T cells in mouse lungs. Periodontitis was performed 14 days before the induction of PH. Samples were analyzed 7 days after PH induction. a, b Representative flow cytometry plots of CD4+IFNγ+ T cells a and quantification of the percentage of CD45+ cells and number of CD4+IFNγ+ T cells b in lungs. n = 9:6. c, d Representative flow cytometry plots of CD8+IFNγ+ T cells c and quantification of the percentage of CD45+ cells and number of CD8+IFNγ+ T cells d in lungs. n = 9:6. e, f Representative flow cytometry plots of CD4+IFNγ+ T cells e and quantification of the percentage of CD45+ cells and number of CD4+IFNγ+ T cells f in cervical lymph nodes (cLNs). n = 8:7. g, h Representative flow cytometry plots of CD8+IFNγ+ T cells g and quantification of the percentage of CD45+ cells and number of CD8+IFNγ+ T cells h in cLNs. n = 8:7. Data are presented as mean ± SEM. Student’s t test b, d, f, h was used for statistical analysis. ns not significant. *P < 0.05. **P < 0.01

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