Fig. 9 | International Journal of Oral Science

Fig. 9

From: Integrative single-cell and bulk transcriptomes analyses reveals heterogeneity of serine-glycine-one-carbon metabolism with distinct prognoses and therapeutic vulnerabilities in HNSCC

Fig. 9

IMPDH inhibitor represses HNSCC tumor growth in vivo. a Representative images of primary tumors appearance in nude mice. The weights (b) and volumes (c) of primary tumors taken from node mice. d The weights of nude mice. e Pictures and quantifications of NPM1, cytochrome-c, and P53 expressions examined by IHC staining in tumor sections of nude mice. f Representative images of primary tumors appearance in nude mice. The weights (g) and volumes (h) of primary tumors taken from node mice. i The weights of nude mice. Mean ± s.d.; ns: not significant, *P < 0.05, compared with DMSO treatment; Student’s t tests

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