Fig. 2 | International Journal of Oral Science

Fig. 2

From: Osteomodulin modulates the inflammatory responses via the interleukin-1 receptor 1/nuclear factor-κB signaling pathway in dental pulpitis

Fig. 2

OMD suppressed the proinflammatory factor production of hDPSCs induced by LPS. a and b RT-qPCR analysis measuring the changes in mRNA expression of IL-1β and TNFα in hDPSCs cultured with 1 μg/mL of LPS and 0–1 μg/mL of rhOMD for 24 h. c WB assay showing the changes in protein levels of IL-1β and TNFα. d Quantitative analysis of the protein expression in (c). e and f Visualization of the expression of IL-1β and TNFα in hDPSCs treated with 1 μg/mL of LPS alone or combined application of 1 μg/mL of LPS and 1 μg/mL of rhOMD using cell immunofluorescence assay (scale bar: 50 μm). The results are expressed as mean ± SD (*P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.000 1)

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