Fig. 7 | International Journal of Oral Science

Fig. 7

From: Osteomodulin modulates the inflammatory responses via the interleukin-1 receptor 1/nuclear factor-κB signaling pathway in dental pulpitis

Fig. 7

Schematic illustration of the OMD-induced regulation in hDPSCs upon LPS stimulation. OMD suppressed the LPS-induced inflammatory process, decreasing the secretion of proinflammatory factors and the activation of NLRP3 inflammasome. OMD may interact with the membrane receptor of IL1R1 and inhibit the NF-κB signaling pathway to exert a protective role during pulpal inflammation

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