Fig. 1 | International Journal of Oral Science

Fig. 1

From: Profiling and functional characterization of long noncoding RNAs during human tooth development

Fig. 1

Identification of lncRNAs in developing fetal teeth. a Schematic diagram of bulk RNA-seq samples from dental epithelium (DE) and dental mesenchyme (DM) of developing fetal teeth at the late bud, cap, and early bell stages. n = 3 per group. gw gestational week. b Boxplots showing the expression (FPKM) of KRT5 and VIM in DE and DM across the three developmental stages, through bulk RNA-seq. c Pie graph showing the quantity of robustly expressed mRNAs and lncRNAs. The number of genes expressed in DE and DM across the three developmental stages is also shown. d Cumulative expression plots comparing the number of mRNAs (left) and lncRNAs (right), that constitute the total sum of gene expression (FPKM), respectively. Percentage of total lncRNA expression (FPKM) accounted for by the union of the top 12 most highly expressed lncRNAs in DE (e) and DM (f)

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