Fig. 3

The composition of the oral microbial community altered in aged mice. a Hierarchical clustered species level heatmap plotted based on log2 transformed group mean relative abundance. The columns represent the study groups, and the rows represent each species annotated with the corresponding phylum level rank on the side. b Dotplots of differentially abundant taxa by pairwise LEfSe analysis. Dot size represents the negative values of the log10 of P values, and bigger dots represent smaller p values. No differential markers were identified between the WT-Young and KO-Young groups; therefore, the figure does not show the comparison