Fig. 2
From: Single-cell spatial atlas of smoking-induced changes in human gingival tissues
Smoking-induced damage in gingival epithelial cells. a Spatial map of the four subgroups of epithelial cells in the Visium HD date. b Spatial map of marker gene expression in the four cell subgroups. c Dot plots showing upregulated pathways in epithelial cells from the SP group. d Visium HD data analysis revealing the expression of KRT1, DSG1, PI3, and GPX2 in the gingival tissue; scale bar = 200 µm. e RT–qPCR analysis of the KRT1, DSG1, PI3, and GPX2 expression levels in epithelial cells treated with LPS and nicotine (n = 3). *P < 0.05
