Fig. 4
From: Single-cell spatial atlas of smoking-induced changes in human gingival tissues
Smoking induces an immune microenvironment disruption by promoting macrophage dysfunction. a Map showing the infiltration of the four immune cell subgroups into the gingiva. b Proportions of each immune cell subgroup in each group. c CellChat analysis revealing outgoing signalling patterns of each immune cell subgroup in each group. d GO analysis of highly expressed genes in macrophages (SP group vs. P group). e GO analysis of downregulated genes in macrophages (SP group vs. P group). f Spatial analysis revealing the spatial relationship of macrophages and endothelial cells. g Visium HD data showing the spatial map of macrophages and endothelial cells
