Fig. 3: Change in log2 anti-S antibody AUC from baseline to the two longest follow-up windows for participants recovered from a prior COVID-19 infection and those naive to COVID-19.

Box plots of the change in anti-S antibody AUC between baseline and third visit (A) and between the third (42–68 days after first vaccine) and fourth visits (70–103 days after first vaccine) (panel B) are shown for participants naive to and recovered from a prior COVID-19 infection. The box indicates interquartile range (IQR = Q–Q1); midline indicates the median. Whiskers are minimum or maximum without outliers. The outliers are the numbers that are below Q1 − 1.5*IQR or above Q3 + 1.5*IQR.