Table 1 Demographic characteristics and biomarkers of the study population.

From: Geographical approach analysis of the impact of air pollution on newborn intrauterine growth and cord blood DNA damage in Mexico City

Participants with georeferenced location (n)

190

Maternal Characteristics

 Age (years, mean ± SD)

28.1 ± 5.1

 Parity (previous pregnancies, mean ± SD)

1.9 ± 1.1

Occupation, n (%)

 Housewife

90 (47.4%)

 Employed

99 (52.1%)

 Non reported

1 (0.5%)

Self-reported secondhand smoke exposure, n (%)

 Yes

93 (49%)

 No

95 (50%)

 Non reported

2 (1%)

Positive urine cotinine test for active tobacco smoke exposure

None

Neonate anthropometry

 Gestational age (weeks, mean ± SD)

38.9 ± 1.2

 Weight (grams, mean ± SD)

3127 ± 439.4

 Length (centimeters, mean ± SD)

49.9 ± 1.2

 APGAR 5 min (mean ± SD)

8.9 ± 0.3

Sex, n (%)

 Female

92 (48.42%)

 Male

95 (50.0%)

 Non reported

3 (2%)

Biomarkers (n)

136

 PAH-DNA adducts/108 nucleotides

  Maternal blood (median ± IQR)

0.98 [0.44, 1.54]

  Cord Blood (median ± IQR)

1.02a [0.58, 1.89]

Cord blood/Maternal blood adduct Ratio (CMR), n (%)

 CMR > 1

82 (60.30%)

 CMR ≤ 1

54 (39.70%)

Spearman correlation (rho coefficient, p-value)

 Maternal vs Cord Blood adducts

0.56 < 0.0001

  1. SD Standard Deviation, IQR Interquartile Range.
  2. aNon-Parametric Wilcoxon Paired Test: p = 0.0028.