Fig. 3: Summary of health outcome categories of the included studies. | Journal of Exposure Science & Environmental Epidemiology

Fig. 3: Summary of health outcome categories of the included studies.

From: Applications of mixture methods in epidemiological studies investigating the health impact of persistent organic pollutants exposures: a scoping review

Fig. 3

A Heat map of health outcome categories by POP class in the included studies. Numbers represent the number of publications where the associations between POP class (rows) and health outcome categories (columns) were examined. Note: Two studies examined two outcome categories together (endocrine and metabolic, hepatic and metabolic). B The five most frequently observed health outcomes of the “Body weight, size and growth” and “Nervous” outcome categories. Note: Each study included multiple outcomes. Chemical class: individual chemicals in each POP class from the 240 included studies are in Supplementary Table S6. POP persistent organic pollutants, PFAS per- and polyfluoroalkyl substances, PBDE polybrominated diphenyl ethers, OCP organochlorine pesticides, PCB polychlorinated biphenyls, PCDD/Fs polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs), BMI body mass index, ADHD attention-deficit/hyperactivity disorder, ASD autism spectrum disorder, IQ intelligence quotient.

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