Table 2 Trends of PFAS concentrations, reported as median and interquartile range (IQR), and trends in GFR, reported as mean and standard deviations (SD).
From: Longitudinal and cross-sectional analysis of perfluoroalkyl substances and kidney function
Variables | Age 70 N = 997 | Age 75 N = 814 | Age 80 N = 601 |
---|---|---|---|
PFAS concentration | Median (IQR) | Median (IQR) | Median (IQR) |
PFHpA, ng/ml | 0.05 (0.03, 0.09) | 0.07 (0.04, 0.11) | 0.03 (0.01, 0.06) |
PFOA, ng/ml | 3.32 (2.54, 4.40) | 3.8 (2.71, 5.41) | 2.53 (1.82, 3.61) |
PFNA, ng/ml | 0.71 (0.53, 0.97) | 1.07 (0.74, 1.59) | 0.87 (0.62, 1.28) |
PFDA, ng/ml | 0.31 (0.24, 0.04) | 0.43 (0.31, 0.62) | 0.33 (0.24, 0.47) |
PFUnDA, ng/ml | 0.28 (0.22, 0.37) | 0.44 (0.33, 0.63) | 0.36 (0.26, 0.53) |
PFHxS, ng/ml | 2.09 (1.61, 3.46) | 3.24 (2.05, 6.26) | 2.87 (1.8, 10.46) |
L-PFOS, ng/ml | 13.31 (10.09, 17.89) | 12.52 (7.96, 19.19) | 7.57 (5.34, 11.48) |
PFOSA, ng/ml | 0.11 (0.08, 0.17) | 0.07 (0.04, 0.13) | 0.01 (0.02, 0.05) |
Kidney function | Mean (+/−SD) | Mean (+/−SD) | Mean (+/−SD) |
GFR, ml/min/1.73 m2 | 86.33 (13.67) | 70.82 (13.67) | 62.16 (14.67) |