Table 3 Associations between the baseline PFAS concentrations and the change in eGFR over time following adjustment for age (time), BMI, smoking, HDL- and LDL-cholesterol, triglycerides, glucose, and statin use.

From: Longitudinal and cross-sectional analysis of perfluoroalkyl substances and kidney function

PFAS

Main effect (β), 95% CI

Interaction effect (β), 95% CI

PFHpA

−0.842 (−1.869, 0.184)

0.357 (−1.983, 2.699)

PFHxS

1.128 (0.159, 2.096)

0.029 (−1.979, 2.038)

PFOA

1.702 (0.326, 3.078)

0.446 (−2.628, 3.521)

PFNA

3.593 (2.274, 4.912)

−1.891 (−4.818, 1.037)

PFDA

3.586 (1.656, 5.516)

−2.125 (−6.100, 1.852)

PFOSA

−3.722 (−4.805, −2.640)

5.805 (3.334, 8.277)

PFUnDA

4.377 (2.586, 6.169)

−3.090 (−6.912, 0.732)

L-PFOS

1.143 (0.278, 2.008)

0.625 (−1.377, 2.627)

  1. BMI Body Mass Index, HDL High-Density Lipoprotein, LDL Low-Density Lipoprotein cholesterol, β Beta coefficient, CI confidence interval.