Table 1 Differences in methods between the 2011 and 2019 NICE guideline systematic reviews.
2011 Review [1] | 2011 Review (sensitivity analysis) [1] | 2019 Review [4] | |
|---|---|---|---|
Population | Adults | Adults (excluding studies with low-mean BP, i.e., excluding normotensive sample) | Adults with suspected hypertension |
Target condition | Hypertension | Hypertension | Hypertension |
Index tests | • Home BP • Clinic BP | • Home BP • Clinic BP | • Home BP without telemonitoring • Home BP with telemonitoring • Clinic BP • Pharmacy monitoring |
Reference standard | Ambulatory BP (threshold 135/85 mmHg) | Ambulatory BP (threshold 135/85 mmHg) | Ambulatory BP (threshold 135/85 mmHg) |
Outcomes | • Sensitivity • Specificity • Raw data to calculate 2 × 2 data | • Sensitivity • Specificity • Raw data to calculate 2 × 2 data | • Sensitivity • Specificity • Raw data to calculate 2 × 2 data • Studies where 2 × 2 data couldn’t be derived were included but not meta-analysed |
Search strategy (data limits) | 1950 onwards | 1950 onwards | 2000 onwards |
Other exclusion criteria | • Studies where 2 × 2 data couldn’t be derived • Home with telemonitoring | • Studies where 2 × 2 data couldn’t be derived • Home with telemonitoring | – People with: • Established (already diagnosed) hypertension • Type-2 diabetes • Established cardiovascular disease • Chronic kidney disease |
