Table 5 Quantitative impact of CV risk factors on global work index (GWI), measured in mmHg%.
From: Impact of cardiovascular risk factors on myocardial work—insights from the STAAB cohort study
Univariable model | Interaction with sex | Adjusted for age and sex | Adjusted for age, sex, systolic blood pressure | |||||
|---|---|---|---|---|---|---|---|---|
Δ (95% CI) | P value | P value | Sex | Δ (95% CI) | P value | Δ (95% CI) | P value | |
Body mass index [kg/m2] | −5 (−9 to −1) | 0.019 | 0.002 | M | −13 (−19 to −7)a | <0.001 | –14 (–17 to –11) | <0.001 |
F | −0.1 (−5 to +5) | 0.968 | ||||||
Systolic blood pressure [mmHg] | +14 (+14 to +15) | <0.001 | 0.877 | All | +17 (+16 to +17) | <0.001 | – | – |
Total cholesterol [mg/dl] | +0.8 (+0.3 to +1) | 0.001 | 0.862 | All | +0.3 (−0.1 to +0.8) | 0.163 | – | – |
LDL cholesterol [mg/dl] | +0.2 (−0.3 to +0.7) | 0.481 | 0.794 | All | −0.005 (−0.5 to +0.5) | 0.984 | – | – |
HbA1c [%] | −2 (−34 to +30) | 0.917 | 0.435 | All | −46 (−79 to −12) | 0.008 | –80 (–104 to –56) | <0.001 |
Glucose level [mmol/L] | −3 (−21 to +16) | 0.776 | 0.974 | All | −8 (−27 to +10) | 0.383 | – | – |
Glucose level after 2 h [mmol/L] | +31 (+18 to +43) | <0.001 | 0.985 | All | +24 (+12 to +37) | <0.001 | – | – |
Diabetes | −20 (−84 to +45) | 0.552 | 0.696 | All | −53 (−118 to +12) | 0.108 | – | – |
Hypertension | +253 (+219 to + 287) | <0.001 | 0.046 | M | +240 (+190 to +288)a | <0.001 | – | – |
F | +307 (+256 to +358) | <0.001 | ||||||
Smoking | −160 (−204 to −116) | <0.001 | 0.827 | All | −140 (−184 to −97) | <0.001 | −58 (−90 to −26) | <0.001 |
Obesity | −82 (−131 to −34) | 0.001 | 0.349 | All | −95 (−143 to −48) | <0.001 | M: −115 (−161 to −69)b | <0.001 |
F: −184 (−233 to −134) | <0.001 | |||||||
Dyslipidaemia | −30 (−82 to +22) | 0.256 | 0.908 | All | −77 (−130 to −23) | 0.005 | −73 (−111 to −35) | <0.001 |
