Table 3 (a) Calculation of average antihypertensive drug requirement per patient per month in a number of pills, protocol 1 (AATTC), scenario 1. (b) Estimated antihypertensive drug requirement per patient in a number of pills.
Monthly antihypertensive drug requirement matrix of 100 patients | ||||||||
|---|---|---|---|---|---|---|---|---|
Treatment Stage | Expected % control | A5 | 2*A5 | Total A5 requirement | T40 | 2*T40 | Total T40 requirement | CTD 12.5 |
(a) | ||||||||
1 | 30 | 900 | 900 | 0 | ||||
2 | 30 | 900 | 1800 | 0 | ||||
3 | 20 | 600 | 1200 | 600 | 600 | |||
4 | 10 | 300 | 600 | 300 | 600 | |||
5 | 10 | 300 | 600 | 300 | 600 | 300 | ||
Total | 100 | 900 | 2100 | 5100 | 600 | 600 | 1800 | 300 |
(b) | |||||||
|---|---|---|---|---|---|---|---|
A5 | 2*A5 | Total A5 requirement | T40 | 2*T40 | Total T40 requirement | CTD 12.5 | |
Monthly requirement | 9 | 21 | 51 | 6 | 6 | 18 | 3 |
Annual requirement | 621 | 219 | 37 | ||||