Fig. 1: Trial profile.

XILO-FIST Xanthine oxidase inhibition for the Improvement of Long-term Outcomes Following Ischemic Stroke and Transient ischemic attack, MRI Magnetic Resonance Imaging, BP Blood Pressure, ABPM Ambulatory Blood Pressure Monitoring. * ABPM data was not received from 12 sites (120 participants). † ABPM was not performed at baseline and week 4 in participants, e.g., due to contraindications or failure to attend. ‡ ABPM readings were excluded if either baseline or week 4 readings were insufficient (<10 wake or <5 sleep readings). § Of the 196 participants with sufficient baseline and week 4 ABPM readings, 115 participants had sufficient week 104 readings (54 allopurinol: 61 placebo).