Table 3 Change in short-term (ABPM) blood pressure variability from baseline to week 4.
BP Parameter | Change with placebo | Change with allopurinol | Unadjusted between group difference | P value | Adjusted between group difference | P value |
|---|---|---|---|---|---|---|
n = 100, | n = 96, | (95% CI) | (95% CI) | |||
mean ± SD | mean ± SD | |||||
SBPMean (mmHg) | 0.4 ± 9.5 | –1.8 ± 11.2 | 2.20 (–0.73, 5.13) | 0.141 | ||
SBPRange (mmHg) | 2.3 ± 18.6 | –1.5 ± 17.1 | 3.72 (–1.31, 8.75) | 0.147 | 2.54 (–2.28, 7.36) | 0.301 |
SBPSD (mmHg) | 0.8 ± 3.9 | –0.5 ± 4.0 | 1.30 (0.18, 2.42) | 0.023 | 1.09 (–0.01, 2.19) | 0.051 |
SBPARV (mmHg) | 0.8 ± 3.1 | –0.5 ± 3.4 | 1.31 (0.31, 2.32) | 0.011 | 1.09 (0.12, 2.05) | 0.028 |
SBPCV (%) | 0.5 ± 3.1 | –0.2 ± 3.1 | 0.72 (–0.15, 1.59) | 0.106 | 0.78 (–0.10, 1.65) | 0.084 |
SBPVIM (units) | 0.6 ± 3.7 | –0.4 ± 3.9 | 0.95 (–0.13, 2.03) | 0.083 | 0.95 (–0.14, 2.03) | 0.087 |
DBPMean (mmHg) | –0.2 ± 3.9 | –0.8 ± 5.9 | 0.61 (–0.80, 2.03) | 0.392 | ||
DBPRange (mmHg) | 0.1 ± 13.6 | –0.8 ± 14.6 | 0.94 (–3.03, 4.92) | 0.641 | 0.82 (–3.17, 4.80) | 0.686 |
DBPSD (mmHg) | –0.1 ± 2.7 | –0.1 ± 2.9 | 0.01 (–0.79, 2.01) | 0.984 | 0.00 (–0.80. 0.79) | 0.992 |
DBPARV (mmHg) | 0.1 ± 2.3 | –0.2 ± 2.6 | 0.25 (–0.51, 1.01) | 0.514 | 0.23 (–0.53, 0.99) | 0.550 |
DBPCV (%) | –0.1 ± 3.7 | 0.0 ± 4.2 | –0.17 (–1.28, 0.95) | 0.771 | –0.08 (–1.19, 1.02) | 0.881 |
DBPVIM (units) | –0.2 ± 2.7 | –0.1 ± 3.0 | –0.11 (0.91, 0.69) | 0.782 | –0.08 (–0.88, 0.73) | 0.853 |
