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Outcomes in gastroschisis: expectations in the postnatal period for simple vs complex gastroschisis

Journal of Perinatology volume 41, pages 1755–1759 (2021)Cite this article

Subjects

Abstract

Objective

To provide generalizable estimates for expected outcomes of simple gastroschisis (SG) and complex gastroschisis (CG) patients from a large multi-institutional cohort for use during counseling.

Study design

A retrospective study of 394 neonates with gastroschisis at 11 children’s hospitals from January 2013 to March 2017 was performed. Analysis by Fisher’s exact tests and Wilcoxon rank sum tests were performed. Outcomes of complex and simple gastroschisis are reported.

Result

There were 315 (80%) SG and 79 (20%) CG. CG had increased time from birth to closure (6 vs 4.4 days), closure to goal feeds (69 vs 23 days), ventilator use (90% vs 73%), SSIs (31% vs 11%), NEC (14% vs 6%), PN use (71 vs 24 days), LOS (104.5 vs 33 days), and mortality (11% vs 0%).

Conclusion

This study provides generalizable estimates for expected outcomes of patients with both SG and CG that can be utilized during counseling. CG has significantly worse in-hospital outcomes.

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Author information

Authors and Affiliations

  1. Department of Surgery, Children’s Mercy Kansas City, Kansas City, MO, USA

    Charlene Dekonenko, Jason D. Fraser & Shawn D. St. Peter

  2. Center for Surgical Outcomes Research, Abigail Wexner Research Institute, Nationwide Children’s Hospital, Columbus, OH, USA

    Katherine J. Deans, Amy E. Lawrence & Peter C. Minneci

  3. Department of Surgery, Nationwide Children’s Hospital, Columbus, OH, USA

    Katherine J. Deans, Amy E. Lawrence & Peter C. Minneci

  4. Department of Surgery, University of Louisville Norton Children’s Hospital, Louisville, KY, USA

    Mary E. Fallat, Cynthia Downard & Tiffany N. Wright

  5. Department of Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

    Michael Helmrath & Beth Rymeski

  6. Department of Surgery, Northwestern University Lurie Children’s Hospital, Chicago, IL, USA

    Rashmi Kabre, Kristine Corkumd & Julia E. Grabowski

  7. Department of Surgery, University of Wisconsin American Family Children’s Hospital, Madison, WI, USA

    Charles M. Leys & Jonathan E. Kohler

  8. Department of Surgery, Indiana University Riley Hospital for Children, Indianapolis, IN, USA

    R. Cartland Burns, Edward Hernandez & Matthew P. Landman

  9. Department of Surgery, Washington University St. Louis Children’s Hospital, St. Louis, MO, USA

    Patrick A. Dillon

  10. Department of Surgery, University of Michigan CS Mott Children’s Hospital, Ann Arbor, MI, USA

    Samir K. Gadepalli, Ronald Hirschl & Kevin N. Johnson

  11. Department of Surgery, Children’s Hospital of Wisconsin, Milwaukee, WI, USA

    Rachel M. Landisch & Thomas T. Sato

  12. Department of Surgery, University of Chicago Comer Children’s Hospital, Chicago, IL, USA

    Grace Z. Mak & Bethany J. Slater

Authors
  1. Charlene Dekonenko
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  2. Jason D. Fraser
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  3. Katherine J. Deans
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  4. Mary E. Fallat
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  5. Michael Helmrath
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  6. Rashmi Kabre
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  7. Charles M. Leys
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  8. R. Cartland Burns
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  9. Kristine Corkumd
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  10. Patrick A. Dillon
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  11. Cynthia Downard
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  12. Tiffany N. Wright
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  13. Samir K. Gadepalli
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  14. Julia E. Grabowski
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  15. Edward Hernandez
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  16. Ronald Hirschl
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  17. Kevin N. Johnson
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  18. Jonathan E. Kohler
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  19. Matthew P. Landman
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  20. Rachel M. Landisch
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  21. Amy E. Lawrence
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  22. Grace Z. Mak
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  23. Peter C. Minneci
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  24. Beth Rymeski
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  25. Thomas T. Sato
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  26. Bethany J. Slater
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  27. Shawn D. St. Peter
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Corresponding author

Correspondence to Shawn D. St. Peter.

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Conflict of interest

CD receives monetary reimbursement associated with costs incurred for presenting gastroschisis research at symposia which is provided by the Avery’s Angels Foundation, an organization that supports gastroschisis research.

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Dekonenko, C., Fraser, J.D., Deans, K.J. et al. Outcomes in gastroschisis: expectations in the postnatal period for simple vs complex gastroschisis. J Perinatol 41, 1755–1759 (2021). https://doi.org/10.1038/s41372-021-01093-8

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  • DOI: https://doi.org/10.1038/s41372-021-01093-8

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