Table 1 Pre- and post-paracetamol treatment echocardiography measurements.
From: The effect of patent ductus arteriosus treatment with paracetamol on pulmonary vascular resistance
Pre-treatment | Post-treatment | p | |
|---|---|---|---|
Heart rate | 163 ± 17 | 167 ± 14 | 0.52 |
PDA characteristics | |||
PDA diameter (mm) | 3.2 ± 0.8 | 3.0 ± 0.7 | 0.31 |
PDA systolic:diastolic velocity ratio | 5.6 [3.0–6.1] | 3.6 [2.3–5.3] | 0.06 |
LA:Ao | 2.1 ± 0.4 | 1.9 ± 0.4 | 0.14 |
LV end diastolic diameter (mm) | 15 ± 3 | 15 ± 3 | 0.97 |
Descending aorta EDV (m/s) | −0.12 [−0.21 to −0.07] | 0.13 [0.06–0.19] | <0.01 |
Myocardial function | |||
LV ejection fraction (%) | 60 ± 9 | 59 ± 8 | 0.97 |
RV fractional area change (%) | 0.30 ± 0.11 | 0.29 ± 0.12 | 0.76 |
Surrogate PVR markers | |||
PAAT | 44 ± 13 | 38 ± 9 | 0.10 |
PAATi | 0.34 ± 0.09 | 0.25 ± 0.04 | <0.01 |
LV Eccentricity Index | 1.3 ± 0.1 | 1.4 ± 0.2 | 0.049 |