Table 2 Associated factors for neonatal SA sepsis present at the time of positive blood culture.

From: Neonatal Staphylococcus Aureus Sepsis: a 20-year Western Australian experience

Associated Risk Factors

EOS (N = 6) (%)

LOS (N = 56) (%)

GA < 32 weeks (N = 47) (%)

GA ≥ 32 weeks (N = 15) (%)

MSSA (N = 46) (%)

MRSA (N = 16) (%)

Total, N (% of total cohort, N = 62)

Preterm birth < 37 weeks

3 (50%)

53 (95%)

  

40 (87%)

16 (100%)

56 (90%)

Very preterm (28–32 weeks)

0 (0%)

15 (27%)

  

9 (20%)

6 (38%)

15 (24%)

Extremely preterm (<28 weeks)

1 (1%)

31 (55%)

  

23 (50%)

9 (56%)

32 (52%)

Very low birth weight (<1500 g)

1 (1%)

44 (79%)

44 (94%)

1 (7%)

31 (67%)

14 (88%)

45 (73%)

Proven colonised with SA prior to blood culturea

2 (2%)

15 (27%)

16 (34%)

1 (7%)

12 (26%)

5 (31%)

17 (27%)

Central lines in situb

2 (33%)

14 (25%)

12 (26%)

4 (27%)

12 (26%)

4 (25%)

16 (26%)

- UAC

1

1

2

0

1

1

2

- UVC

1

3

2

2

3

1

4

- PICC

0

10

8

2

8

2

10

IV cannula in situb

1 (1%)

33 (59%)

29 (62%)

5 (33%)

23 (50%)

11 (69%)

34 (55%)

ETT in situb

0 (0%)

19 (34%)

19 (40%)

0 (0%)

14 (30%)

5 (31%)

19 (31%)

TPN in situb

0 (0%)

37 (66%)

33 (70%)

4 (27%)

25 (54%)

12 (75%)

37 (60%)

Surgical procedures prior to sepsis

0 (0%)

2 (4%)

1 (2%)

1 (7%)

1 (2%)

1 (6%)

2 (3%)

  1. apositive blood culture for SA
  2. bat time of positive SA on blood culture
  3. EOS early onset sepsis, ETT endotracheal tube, GA gestational age, LOS late onset sepsis (>48 h), MRSA methicillin resistant Staphylococcus aureus, MSSA methicillin susceptible Staphylococcus aureus, N number of cases (%), PICC peripherally inserted central catheter, SA Staphylococcus aureus, TPN total parenteral nutrition, UAC umbilical artery catheter, UVC umbilical vein catheter