Table 1 Demographic and infection characteristics of pregnant persons with SARS-CoV-2 infection by trimester of infection and disease severity.

From: Preterm birth among pregnant persons with severe acute respiratory syndrome Coronavirus 2 infection

 

[Total unweighted number of persons with available information] Weighted %a (95% CI)

  

Trimester in which SARS-CoV-2 infection occurredb

COVID-19 severity

Characteristic

Total

1st

2nd

3rdc

Mild

Moderate-to-severe

Critical

Asymptomatic

Total

[6336]

13.9 (10.9–16.9)

39.5 (35.5–43.5)

46.6 (42.5–50.7)

57.3 (53.1–61.5)

25 (20.8–29.3)

3.5 (2.5–4.5)

14.2 (11.2–17.1)

Age (years)

[6333]

[991]

[2560]

[2782]

[3968]

[1267]

[283]

[815]

Median (IQR)

29.4 (8.1)

28.6 (7.2)

29.9 (8.5)

29.2 (8)

29.2 (7.7)

30.6 (8.1)

32.3 (9)

27.6 (8.3)

 <20

4.7 (3.5–5.9)

4.7 (2.4–7)

4.1 (2.2–5.9)

5.2 (3.2–7.2)

4.1 (3–5.3)

3.9 (1.1–6.6)

8.4 (0–20.7)

7.6 (3.1–12.1)

 20–24

17.7 (15.2–20.2)

22.2 (12.9–31.6)

17.1 (13.2–21)

16.8 (13.7–19.9)

18.6 (15.3–22)

13.3 (9.2–17.3)

6.7 (4.2–9.3)

24.2 (16–32.5)

 25–29

31.3 (27.2–35.4)

30.5 (21.1–40)

29.1 (23–35.2)

33.4 (26.9–39.9)

35 (29.9–40.2)

23.1 (16.9–29.4)

23.8 (11.9–35.7)

32.7 (18.8–46.5)

 30–34

27.8 (24.1–31.5)

30.8 (17.4–44.3)

28 (23.3–32.6)

26.8 (21.3–32.3)

26 (22.9–29.2)

33.7 (22.4–45)

35.5 (22.7–48.3)

22.7 (15.7–29.7)

 35–39

14.9 (11.8–18)

9.3 (6.5–12.2)

17.9 (11.1–24.6)

14.1 (11.2–17)

12.4 (10.2–14.5)

22.6 (12.2–32.9)

21.4 (11–31.8)

10.2 (6.4–14.1)

 40+

3.6 (2.4–4.7)

2.3 (1.2–3.5)

3.8 (1.3–6.4)

3.7 (2.3–5)

3.8 (1.9–5.7)

3.5 (1.7–5.4)

4.2 (2.4–6)

2.6 (1.1–4.1)

Race/ethnicityd

[6150]

[973]

[2482]

[2695]

[3858]

[1229]

[269]

[794]

 Asian, non-Hispanic

4.4 (3.4–5.4)

3.5 (2–5.1)

3.7 (2.2–5.2)

5.2 (3.4–7)

3.9 (2.6–5.1)

4.8 (2.3–7.2)

7.4 (3.8–10.9)

5.1 (1.4–8.7)

 Black, non-Hispanic

13.1 (10.9–15.2)

25.7 (14.4–37.1)

9.8 (8.2–11.3)

12 (9.7–14.3)

14.4 (11.1–17.8)

9 (6.4–11.5)

18.7 (11–26.3)

13.4 (9.5–17.3)

 Hispanic or Latino

52.2 (48.4–56)

44.9 (32.6–57.3)

52.2 (46–58.4)

54.4 (48.9–59.9)

47.5 (42.8–52.2)

55.7 (46–65.6)

60 (48.1–71.9)

62.6 (53.5–71.7)

 White, non-Hispanic

27.7 (24.7–30.6)

23.6 (17.6–29.7)

31.6 (26–37.2)

25.5 (21.7–29.4)

31 (27.4–34.6)

28.5 (20.2–36.8)

12.9 (8–17.9)

16.5 (11.5–21.5)

 Multiple or none of the above, non-Hispanic

2.7 (2–3.4)

2.1 (1.4–2.8)

2.7 (1.6–3.9)

2.9 (1.7–4)

3.2 (2–4.3)

2 (0.9–3.1)

1 (0.3–1.8)

2.5 (1.3–3.7)

Health insurance at delivery

[4745]

[680]

[1843]

[2222]

[2674]

[1107]

[180]

[784]

 Private

45.7 (40.9–50.5)

44.1 (29–59.2)

47.7 (40.1–55.4)

44.4 (37.8–51)

48.4 (42.7–54.1)

43.5 (32–55)

41.1 (23.9–58.3)

41 (28.1–53.9)

 Medicaid

50.8 (46–55.5)

53.5 (38.7–68.3)

47.9 (40.6–55.1)

52.4 (45.8–59)

48.8 (43.2–54.5)

51.7 (40.3–63)

54.5 (37.4–71.7)

55 (42.7–67.4)

 Other/Self-pay/none

3.6 (2.2–4.9)

2.4 (1.4–3.5)

4.4 (1.4–7.4)

3.2 (1.9–4.5)

2.8 (2–3.6)

4.8 (0.3–9.4)

3.9 (2–5.9)

3.9 (2–5.9)

 Maternal education

[4820]

[842]

[2018]

[1960]

[3256]

[922]

[191]

[451]

 Less than high school

12.2 (10.5–14)

11.3 (7.4–15.2)

11.1 (8.3–13.9)

13.8 (11.1–16.6)

12.6 (10.4–14.9)

11.1 (7.7–14.4)

22.3 (18.2–26.5)

10.1 (5.1–15.1)

 High school

29.8 (25.2–34.4)

26 (17.4–34.6)

27.5 (22.2–32.8)

33.8 (25–42.5)

26.4 (22.9–30)

29.8 (19.9–39.7)

28.6 (23–34.2)

48.7 (28.1–69.3)

 Some college

29.4 (24.7–34.1)

38.4 (27.3–49.4)

24.9 (19.8–30)

30.3 (21.7–39)

29.5 (24.9–34.2)

32.7 (19–46.4)

25.9 (19.6–32.2)

22.8 (12.3–33.2)

 College or greater

28.6 (24–33.1)

24.4 (19.2–29.6)

36.5 (28–45)

22.1 (17.9–26.2)

31.4 (25.7–37.1)

26.4 (16.6–36.3)

23.2 (16.9–29.4)

18.4 (10–26.8)

Underlying medical conditions

[5968]

[954]

[2405]

[2609]

[3778]

[1191]

[267]

[732]

 Anye

37.5 (33.8–41.2)

29.2 (21.7–36.7)

41.8 (35.4–48.3)

36.5 (31.3–41.7)

35.4 (31.4–39.6)

43.2 (32.7–53.7)

45.2 (32–58.4)

33.7 (23.8–43.6)

 Prepregnancy obesityf

36.5 (33.2–39.8)

26.9 (21.1–32.6)

39.6 (33.7–45.5)

37.2 (33.2–41.3)

34.9 (31.1–38.8)

41.6 (33–50.2)

44.5 (33.5–55.5)

32.9 (24.8–41)

 Chronic lung disease

13.7 (10.7–16.7)

12 (6.7–17.3)

13.3 (8–18.6)

14.5 (10.1–18.9)

11.3 (8.5–14)

18 (9.9–26.1)

12.4 (5.2–19.7)

14.6 (5.3–23.9)

 Chronic hypertension

3.9 (3.2–4.7)

3.8 (2.1–5.5)

3.9 (2.9–4.8)

4.1 (2.7–5.4)

3.6 (2.8–4.4)

3.5 (2–4.9)

6.8 (3.6–10.1)

5.3 (1.7–8.9)

 Diabetes mellitus type 1 or 2

3.1 (1.7–4.5)

1.3 (0.8–1.8)

3.6 (0.7–6.5)

3.2 (1.6–4.9)

1.6 (1.1–2.1)

6 (1.1–10.9)

4.1 (1.6–6.6)

3.8 (0–7.7)

 Cardiovascular disease

3.1 (2–4.2)

1.9 (0.7–3.1)

4.5 (1.7–7.2)

2.3 (1.5–3.1)

2.4 (1.7–3.1)

3.8 (0.8–6.7)

16.5 (0–35.1)

1.3 (0.5–2)

 Immunosuppression

1.4 (1–1.8)

1.9 (0.4–3.3)

2 (1–3.1)

0.8 (0.6–1.1)

1.8 (1.1–2.6)

0.5 (0.2–0.9)

4.2 (1–7.4)

0.8 (0–1.6)

 Pregnancy-related condition

[5929]

[950]

[2408]

[2571]

[3760]

[1187]

[266]

[716]

 Gestational diabetes

12.3 (9.2–15.4)

12.2 (5.3–19.2)

14.7 (8–21.4)

10.3 (8–12.5)

11.3 (8.5–14.1)

15.8 (5.6–26)

18.6 (10.4–26.8)

8.9 (4.5–13.2)

 Hypertensive disorders in pregnancyg

13.1 (10.8–15.4)

16.6 (8.5–24.7)

13.6 (9.7–17.5)

11.6 (8.9–14.2)

12.8 (9.9–15.7)

12.4 (7.8–16.9)

11.6 (6.7–16.6)

15.7 (7.9–23.6)

Delivery status

[6336]

[992]

[2561]

[2783]

[3969]

[1268]

[283]

[816]

 Term

89 (87.4–90.6)

92.6 (90.1–95)

90.7 (88.2–93.1)

86.6 (83.9–89.3)

92.4 (91.1–93.7)

90 (86.4–93.5)

62.5 (49.7–75.4)

80.3 (73.3–87.2)

 Preterm

11 (9.4–12.6)

7.4 (5–9.9)

9.3 (6.9–11.8)

13.4 (10.7–16.1)

7.6 (6.3–8.9)

10 (6.5–13.6)

37.5 (24.6–50.3)

19.7 (12.8–26.7)

  Extremely preterm (22–27 weeks)

5.5 (1.2–9.7)

7.2 (3.3–11)

14.2 (2.5–25.9)

–

2.3 (1.3–3.4)

2.7 (0.8–4.6)

22.3 (0–50.1)

4.9 (0.1–9.6)

  Early preterm (28–31 weeks)

9.6 (5.1–14.1)

5.7 (2.1–9.4)

17.2 (5.6–29)

5.8 (3.4–8.1)

7.2 (3.6–10.7)

7.3 (1.5–13.2)

13.2 (6.7–19.7)

13.7 (0–28.8)

  Moderately preterm (32–33 weeks)

9.7 (5.9–13.5)

10.1 (5.1–15.2)

7.4 (4–10.7)

11 (4.7–17.3)

9.6 (5.2–13.9)

12.7 (0–26.4)

14.8 (6.4–23.2)

4.8 (2.5–7)

  Late preterm (34–36 weeks)

75.3 (68.8–81.7)

77 (69.3–84.7)

61.2 (48–74.4)

83.3 (76.7–89.9)

80.9 (75.5–86.4)

77.2 (63.1–91.3)

29.7 (29.2–70.2)

76.7 (61.5–91.8)

  Trimester in which SARS-CoV-2 infection occurred

[6336]

–

–

–

[3969]

[1268]

[283]

[816]

 First

13.9 (10.9–16.9)

–

–

–

16.9 (13.6–20.1)

12.9 (3.7–22.1)

3.6 (2.4–4.8)

6.4 (4.4–8.4)

 Second

39.5 (35.5–43.5)

–

–

–

39.4 (34.8–43.9)

44 (33.5–54.4)

44.4 (30.2–58.5)

30.9 (21.8–40)

 Thirdc

46.6 (42.5–50.7)

–

–

–

43.7 (39.1–48.3)

43.1 (32.9–53.3)

52.1 (38.3–65.9)

62.7 (52.9–72.5)

Severity of COVID-19

[6336]

[992]

[2561]

[2783]

    

 Mild

57.3 (53.1–61.5)

69.4 (55.9–82.9)

57.2 (50.6–63.7)

53.9 (47.8–59.9)

–

–

–

–

 Moderate-to-severe

25 (20.8–29.3)

23.2 (8.8–37.6)

27.8 (21–34.7)

23.1 (17.6–28.7)

–

–

–

–

 Critical

3.5 (2.6–4.5)

0.9 (0.6–1.2)

3.9 (2–5.9)

3.9 (2.7–5.2)

–

–

–

–

 Asymptomatic

14.2 (11.2–17.1)

6.5 (4.4–8.6)

11 (7.9–14.3)

19 (13.5–24.6)

    
  1. SARS-CoV-2 severe acute respiratory syndrome coronavirus 2, COVID-19 coronavirus disease 2019.
  2. aPercentages may not sum to 100 due to rounding.
  3. bBased on date of first positive test.
  4. cExcludes persons infected at ≥37 weeks.
  5. dPregnant persons with reported race and ethnicity information were grouped as Hispanic or non-Hispanic White, Asian, Black, multiple, or other. Multiple or other race/ethnicity contains American Indian or Alaska Native, Native Hawaiian or other Pacific Islander, other race as reported by jurisdictions, and more than one race indicated. Pregnant persons with missing or unknown ethnicity and non-Hispanic ethnicity with missing race were considered missing race/ethnicity.
  6. eIncludes one or more of the following underlying medical conditions: prepregnancy obesity, chronic lung disease, chronic hypertension, diabetes mellitus type 1 or 2, cardiovascular disease, and immunosuppression.
  7. fPrepregnancy obesity defined as body mass index ≥30 kg/m2.
  8. gIncludes pregnancy-induced hypertension (gestational hypertension), preeclampsia, eclampsia, and hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome.
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