Table 2 Results of univariate analysis of associations between maternal and gestational conditions and preterm milk macronutrient content at different time points (n = 277).

From: Influence of maternal and perinatal factors on macronutrient content of very preterm human milk during the first weeks after birth

Nutrient

Condition

Time point

 

Concentration

95% CI

of difference

p-value

Protein

in g/dl

Maternal

Age

(years old)

Week 1

<35

1.5 ± 0.3

0.005–0.240

0.043

≥35

1.6 ± 0.3

1st 4 weeks of lactation

<35

1.3 ± 0.2

0.023–0.211

0.022

≥35

1.4 ± 0.3

BMI

(kg/m2)

Week 4

<25

1.1 ± 0.2

0.020–0.183

0.010

≥25

1.2 ± 0.2

Gestational

Multiple

Week 1

Yes

1.4 ± 0.3

0.007–0.302

0.003

No

1.5 ± 0.3

Week 4

Yes

1.0 ± 0.1

0.098–0.221

<0.001

No

1.1 ± 0.2

1st 4 weeks of lactation

Yes

1.2 ± 0.3

0.004–0.244

0.001

No

1.4 ± 0.2

IUGR

Week 4

Yes

1.2 ± 0.2

(−0.230)-(−0.045)

0.010

No

1.1 ± 0.2

1st 4 weeks of lactation

Yes

1.4 ± 0.3

(−0.235)-(−0.006)

0.047

No

1.3 ± 0.2

Hypertensive disorders

Week 4

Yes

1.2 ± 0.2

(−0.221)-(−0.015)

0.043

No

1.1 ± 0.2

Labour and delivery

Labour

Week 4

Yes

1.1 ± 0.2

0.051–0.229

0.004

No

1.2 ± 0.2

Lactation history

Previous lactation

1st 4 weeks of lactation

Yes

1.3 ± 0.3

(−0.028)−0.192

0.029

No

1.4 ± 0.2

Fat

in g/dl

Maternal

BMI

(kg/m2)

Week 4

<25

3.2 ± 0.8

0.067–0.907

0.018

≥25

3.7 ± 0.9

Gestational

Multiple

Week 4

Yes

3.0 ± 0.0

0.22–0.925

0.018

No

3.5 ± 0.9

Hypertensive disorder of pregnancy

Week 1

Yes

3.3 ± 1.2

0.116–1.267

0.019

No

4.0 ± 1.0

Energy

in kJ/dl (in kcal/dl)

Maternal

BMI

(kg/m2)

Week 4

<25

274.2 ± 34.7 (65.6 ± 8.3)

0.663–8.676

0.023

≥25

293.9 ± 35.6 (70.2 ± 8.5)

Gestational

Multiple

Week 4

Yes

262.9 ± 22.2 (62.8 ± 5.3)

2.412–9.266

0.001

No

285.9 ± 36.4 (68.3 ± 8.7)

1st 4 weeks of lactation

Yes

286.3 ± 36.4 (68.4 ± 8.7)

(−1.244) −7.255

0.043

No

298.9 ± 36.4 (71.4 ± 8.7)

Hypertensive disorder of pregnancy

Week 1

Yes

279.6 ± 52.7 (66.8 ± 12.6)

0.243–14.286

0.014

No

309.8 ± 42.3 (74.0 ± 10.1)