Fig. 1: Cumulative numbers of infants eligible for enrollment and families of eligible infants approached for consent in the Pre-COVID-19 baseline epoch; COVID-1 epoch; COVID-2 epoch; Post-COVID -1 epoch; and Post-COVID-2.
From: Adverse effects of COVID-19 pandemic on a multicenter randomized controlled trial
The blue line represents the cumulative increase in the number of infants eligible for enrollment, and the green line represents the cumulative number of parents of eligible infants approached for consent. In the Pre-COVID epoch, 95.4% of parents of eligible infants were approached for consent. From the nadir in COVID-1, the cumulative number of parents of eligible infants approached progressively improved in the subsequent epochs, but only to 84.9% in Post-COVID-2 (p < 0.001 each subsequent epoch compared to Pre-COVID).
