Table 2 Physiological consequences of isolated apneas and sequential apneas at 32–36 weeks PMA, 36–40 weeks PMA, 3- and 6-months CA. Data presented as median [IQR] or N (%).
From: Developmental consequences of short apneas and periodic breathing in preterm infants
32–36 weeks PMA | 36–40 weeks PMA | 3 months CA | 6 months CA | |
|---|---|---|---|---|
Isolated Apneas | ||||
Nadir % change in HR | −7.9 [−10.0, −5.3] | −9.5 [−11.2, −8.1] | −13.1 [−15.5, −11.9] a,b | −16.3 [−18.1, −10.8] a,b |
Nadir % change in SpO2 | −4.5 [−5.5, −2.9] | −2.6 [−5.0, −2.3] | −1.9 [−2.7, −1.4] a,b | −1.7 [−3.1, −1.2] a,b |
Nadir % change in TOI | −2.6 [−3.5, −1.7] | −2.5 [−3.5, −1.5] | −2.3 [−3.2, −1.4] | −2.0 [−3.3, −1.3] |
N spent time in SpO2 < 90% (%) | 25 (96) | 12 (50) | 5 (32) a | 4 (17) a,b |
% TST with SpO2 < 90% | 0.2 [0.1, 0.6] | 0.1 [0.0, 0.4] | 0.0 [0.0, 1.9] | 0.1 [0.0, 0.1] |
N spent time in TOI < 55% (%) | 8 (31) | 6 (25) | 4 (21) | 0 (0) a,b |
% TST with TOI < 55% | 0.2 [0.1, 1.8] | 0.7 [0.1, 1.7] | 0.5 [0.4, 1.2] | - |
Sequential apneas | ||||
Nadir % change in HR | −10.0 [−13.0, −7.4] | −10.8 [−12.9, −7.9] | −16.1 [−18.9, −14.5] a,b | −15.2 [−19.7, −12.9] a,b |
Nadir % change in SpO2 | −5.8 [−8.0, −4.2] | −3.6 [−6.6, −2.3] | −2.5 [−4.1, −1.9] a | −4.2 [−4.4, −2.8] |
Nadir % change in TOI | −3.5 [−4.6, −2.4] | −2.5 [−4.0, −1.8] | −2.5 [−3.9, −1.5] | −2.4 [−5.3, −1.3] |
N spent time in SpO2 < 90% (%) | 22 (88) | 13 (54) | 1 (8) a,b | 3 (30) a |
% TST with SpO2 < 90% | 0.2 [0.1, 0.4] | 0.2 [0.1, 0.4] | - | 0.3 [0.1, 0.4] |
N spent time in TOI < 55% (%) | 7 (28) | 7 (29) | 2 (17) | 1 (10) |
% TST with TOI < 55% | 0.1 [0.0, 0.6] | 0.2 [0.0, 0.6] | 0.5 [0.5, 0.6] | - |
