Table 2 Model build performed for diagnosis indicative of MIA.

From: Assessing for prenatal risk factors associated with infant neurologic morbidity using a multivariate analysis

Variable

Parameter estimate

Standard error

Odds ratio (95% CI)

P-value

Intercept

−17.18

3.16

 

<0.0001

BMI

 <18.5

1.00

0.58

2.71 (0.87–8.49)

0.0871

 25–29.9

0.47

0.36

1.61 (0.79–3.26)

0.1916

 ≥30.0

1.14

0.33

3.14 (1.66–5.95)

0.0004

Gestational age

 <25 weeks

2.22

0.80

9.17 (1.93–43.68)

0.0054

 25–31 weeks

1.96

0.35

7.08 (3.54–14.13)

<0.0001

 32–36 weeks

1.37

0.34

3.92 (2.00–7.70)

<0.0001

sFASL

0.96

0.35

2.61 (1.31–5.20)

0.0062

TRAIL

1.31

0.44

3.70 (1.56–8.78)

0.0030

Adiponectin

0.28

0.07

1.32 (1.14–1.53)

0.0002

M-CSF

 <25th percentile

1.49

0.48

4.44 (1.73–11.42)

0.0019

 >75th percentile

−1.37

0.51

0.26 (0.09–0.69)

0.0072

MIP1B

 <25th percentile

−0.88

0.45

0.42 (0.17–1.00)

0.0498

 >75th percentile

−0.77

0.38

0.46 (0.22–0.97)

0.0403

TGFa

 <25th percentile

1.93

0.50

6.91 (2.59–18.47)

0.0001

 >75th percentile

1.02

0.50

2.77 (1.05–7.33)

0.0397

Leptin

 <25th percentile

−1.17

0.40

0.31 (0.14–0.69)

0.0038

 >75th percentile

−0.40

0.34

0.67 (0.35–1.29)

0.2288

  1. AUC 0.814 (0.763–0.865).
  2. References for categorical variables: BMI - normal; Gestational Age - 37–42 weeks; M-CSF, MIP1B, TGFa, Leptin - 25–75th percentile. All biomarkers natural log transformed.
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