Table 1 Characteristics of infants by inhaled corticosteroid prescription status.
ICS (n = 9253) | No ICS (n = 64,870) | |
|---|---|---|
Cesarean section | 7003 (77) | 49,448 (77) |
Birthweight (grams) | ||
≤500 | 464 (5) | 495 (1) |
501–1000 | 6582 (71) | 19,826 (31) |
1001–1500 | 2207 (24) | 44,549 (69) |
Gestational age (weeks) | ||
<25 | 3939 (43) | 6117 (9) |
26–28 | 4058 (44) | 22,237 (34) |
29–32 | 1256 (14) | 36,516 (56) |
PMA at discharge (weeks) | 40 (38–43) | 37 (35–38) |
Male | 5070 (55) | 31,241 (48) |
Race/ethnicity | ||
White | 3687 (42) | 26,846 (44) |
Black | 2939 (33) | 18,734 (30) |
Hispanic | 1564 (18) | 11,786 (19) |
Other | 583 (7) | 4276 (7) |
Chronic respiratory diseases | ||
Study defined BPD | 6358 (69) | 12,608 (20) |
Provider defined | ||
Pulmonary insufficiency | 4740 (51) | 22,985 (35) |
BPD | 2221 (24) | 3901 (6) |
CLD | 4559 (49) | 9254 (14) |
PPHN | 1024 (11) | 1577 (2) |
Pneumonia | 1294 (14) | 2017 (3) |
Aspiration | 331 (4) | 614 (1) |
RAD/Asthma | 36 (0.4) | 38 (0.1) |
Bronchiolitis/Wheezing | 44 (0.5) | 71 (0.1) |
Tracheobronchomalacia | 56 (0.6) | 72 (0.1) |
Oxygen support | 9101 (98) | 49,476 (76) |
Duration in weeks | 10 (5–15) | 1 (0–4) |
Mechanical ventilation | 7971 (86) | 29,825 (46) |
Duration in weeks | 3 (0–6) | 0 (0–0) |
Other medication use | ||
Antenatal steroid | 8272 (89) | 57,586 (89) |
Surfactant | 7557 (82) | 34,689 (53) |
Montelukast | 7 (0.1) | 3 (0.0) |
Diuretic | 6935 (75) | 15,744 (24) |
Bronchodilator | 4578 (49) | 2657 (4) |
Postnatal systemic steroid | 4572 (49) | 6289 (10) |
