Table 2 Predictors of inhaled corticosteroid prescription in the neonatal intensive care unit.

From: Prescribing practices of inhaled corticosteroids for premature infants in the neonatal intensive care unit

 

Unadjusted OR (95% CI)

Adjusted OR (95% CI)

Risk factors:

Gestational age

 <25 weeks

18.72 (17.47–20.06)

1.66 (1.48–1.87)

 26–28 weeks

5.31 (4.97–5.66)

1.69 (1.54–1.85)

 29–32 weeks

ref

Ref

 Male sex

1.30 (1.25–1.36)

1.16 (1.09–1.24)

Race/ethnicity

 White

ref

ref

 Black

1.14 (1.08–1.20)

0.99 (0.91–1.08)

 Hispanic

0.97 (0.91–1.03)

0.93 (0.84–1.03)

 Other

0.99 (0.90–1.09)

0.86 (0.75–0.99)

 BPD

9.23 (8.79–9.69)

2.50 (2.27–2.75)

Antenatal steroid use

1.07 (0.99–1.14)

1.29 (1.16–1.44)

Mechanical ventilation (weeks)

1.47 (1.46–1.48)

1.02 (1.00–1.04)

Oxygen support (weeks)

1.24 (1.23–1.24)

1.22 (1.20–1.23)

Systemic steroid use (weeks)

1.41 (1.39–1.43)

1.08 (1.06–1.10)

  1. Values reported as odds ratio (95% confidence interval).
  2. PMA postmenstrual age, BPD study defined bronchopulmonary dysplasia. Analysis performed by simple and multivariable logistic regression with backwards selection using variables with p < 0.2 identified by univariable analysis. Bold indicates statistical significance.