Table 3 Maternal and Infant Characteristics of GIFA-positive NEC cases.

From: Molecular testing for gastrointestinal pathogens in intestinal tissue of infants with necrotizing enterocolitis or spontaneous intestinal perforation

Cases

GIFA Pathogen

Blood cultures

GA (weeks)

BW (g)

DOL at diagnosis

PCA (weeks)

NEC Stage/Tissue

Feeding

Sequelae d/t NEC

Maternal parity

Mode of delivery

Chorioamnionitis

1

C. difficile

No growth

31

1755

10

33

IIIb/Colona

formula

none

G2P2

Vaginal

N

2

C. difficile

unknown

32

1513

10

34

IIIb/Cecuma

EBM

SBS

G2P2

C/section

N

3

EAEC

No growth

31

1204

21

34

IIIb/Cecuma

formula

death

G3P3

C/section

N

4

EAEC

CONS

25

715

23

28

IIIb/Cecuma

formula

none

G3P3

Vaginal

Y

5

EAEC

E.coli

34

2597

5

34

IIIb/SIb

EBM

death

G5P5

Vaginal

N

6

G. lamblia

No growth

30

1145

9

31

IIIb/SIb

EBM

death

G2P2

C/section

N

  1. CONS coagulase-negative Staphylococcus, C. difficile clostridioides difficile, EAEC enteroaggregative E.coli, E.coli Escherichia coli, G. lamblia Giardia lamblia, GA gestational age, BW birth weight, DOL day of life, PCA post-conceptual age, SI small intestine, EBM expressed breastmilk, SBS short bowel syndrome, BPD bronchopulmonary dysplasia, C/section Caesarean section
  2. aSurgical specimen
  3. bAutopsy specimen