Table 2 Characteristics of infants who died or had severe illness from episode of E. coli sepsis vs. those who survived till discharge without severe illness from E. coli sepsis.
From: Predictors of mortality and severe illness from Escherichia coli sepsis in neonates
Characteristic | Died or had severe illness from E. coli sepsis (N = 39) | Survived to discharge without severe illness from E. coli sepsis (N = 29) | P value |
|---|---|---|---|
Median GA in weeks (IQR) | 28.5 (25.5, 32.0) | 34.5 (30.0, 38.6) | 0.002 |
Median BW in grams (IQR) | 1100 (770, 1760) | 2410 (1520, 2931) | 0.001 |
Number of VLBW neonates (%) | 24 (61.5%) | 7 (24%) | 0.002 |
Sex, N (%) | |||
Male | 23 (59%) | 20 (70%) | 0.4 |
Female | 16 (41%) | 9 (30%) | |
Race, N (%) | |||
White | 18 (46%) | 10 (34%) | 0.5 |
Black | 20 (51%) | 17 (59%) | |
Other | 1 (3%) | 2 (7%) | |
Delivery type, N (%) | 0.4 | ||
C-section Vaginal | 13 (33%) 26 (67%) | 7 (24%) 22 (76%) | |
Presence of maternal IAI, N (%) | 11 (28%) | 9 (31%) | 0.8 |
Ampicillin resistancea, N (%) | 29/39 (74.4%) | 18/28 (64.3%) | 0.28 |
Gentamicin resistancea, N (%) | 4/39 (10.3%) | 1/28 (3.6%) | 0.3 |
Lowest ANC, median (IQR) | 2.9 (0.9, 5.9) | 4.0 (2.4, 6.2) | 0.8 |
Lowest platelet count, median (IQR) | 97 (70, 164) | 262 (213, 294) | <0.0001 |
EOS (%) | 56% | 55% | 0.90 |
Time of collection of blood culture, median hours (IQR) | 37 (2,168) | 13 (1.5,230) | 0.35 |
Time to positivity of blood culture, median hours (IQR) | 9.75 (8.65, 11.38) | 9.39 (8.54, 10.70) | 0.7 |
Thrombocytopenic, N (%) | 25 (64%) | 4 (14%) | <0.0001 |
Neutropenic, N (%) | 10 (33%) | 4 (14%) | 0.04 |
