Table 3 Characteristics of infants with E. coli early-onset sepsis (EOS) and late-onset sepsis (LOS).

From: Predictors of mortality and severe illness from Escherichia coli sepsis in neonates

 

EOS (N = 38)

LOS (N = 30)

P value

GA

30.1 (27.4,34.3)

32.4 (26.5, 38.3)

0.40

BW

1380 (1021, 2683)

1775 (791, 2889)

0.50

GA < 37 weeks

29/38 (76%)

19/30 (63.3%)

0.24

VLBW (%)

55%

33%

0.071

Sex

  

0.011

 Female

19/38 (50%)

24/30 (80%)

 

Race

  

0.22

Black

White

Other

22

16

0

12

15

3

 

Delivery type

  

0.012

 C-Section

16/38 (42%)

4/30 (13%)

 

Maternal IAI

 Yes

18/38 (49%)

2/30 (7.4%)

<0.001

Ampicillin resistance

 R

28/38 (74%)

19/30 (66%)

0.53

Gentamicin resistance

 R

3/38 (7.9%)

2/30 (6.9%)

>0.9

Mortality

22 (58%)

17 (57%)

0.90

Need for inotropic medication or severe metabolic acidosis

21 (55%)

16 (53%)

0.90

  1. EOS was defined as positive blood or CSF culture within 72 h of birth, and any positive cultures that were obtained after the 72-h period were classified as LOS.
  2. GA gestational age, BW birth weight, VLBW very low birth weight, IAI intra-amniotic infection.