Table 1 Cohort characteristics (n = 94).

From: Association of furosemide versus chlorothiazide exposures with serum sodium, potassium, and chloride among infants with bronchopulmonary dysplasia

Baseline Characteristics

Gestational age, median [IQR], week

25 [23–27]

Birth weight, median [IQR], grams

658 [485–831]

Maternal ethnicity, No. (%)

 Not Hispanic or Latino

78 (83)

 Hispanic or Latino

16 (17)

Maternal race, No. (%)

 White

17 (18)

 Black

42 (45)

 Other or unknown

35 (37)

Sex, No. (%)

 Female

38 (40)

 Male

56 (60)

Clinical Characteristics

Respiratory support at 36 weeks PMA, No (%)

 Non-invasive CPAP

24 (25)

 Non-invasive bi-level support

1 (1)

 Conventional mechanical ventilation

62 (66)

 High frequency ventilation

7 (8)

Novel diuretic exposuresa, No. (%)

 Furosemide

117 (85)

 Chlorothiazide

20 (15)

Novel diuretic exposures per infant, No. (%)

 1 exposure

63 (67)

 2 exposures

25 (27)

 ≥ 3 exposures

6 (6)

  1. IQR interquartile range, PMA post-menstrual age, CPAP continuous positive airway pressure.
  2. aAccounts for total number of novel diuretic exposures within the cohort. Total number of exposures is 137, which exceeds 94 subjects as each subject could contribute multiple exposures if they met criteria.
Back to article page