Table 1 Summary of characteristics of articles included for analysis in systematic review of arm A.
S.No | Author | Year | Study design | Treatment methods explored | Location | Population | N | BW | GA | PP |
|---|---|---|---|---|---|---|---|---|---|---|
1 | Welsh et al. [18] | 1979 | Interventional Lab Experiment | Pasteurization: (62.5 °C for 30 min), Freeze-thawing: (−15 °C for 10 days) | Australia | Mothers | NR | NA | NA | 1 to 28 d pp |
2 | Dworsky et at. [19] | 1982 | Interventional Lab Experiment | Pasteurization: (62 °C for 30 min), Freeze-thawing: (−20 °C for up to 7 days) | US | Mothers | 32 | NA | NA | 2 - 18 wks pp |
3 | Hamprecht et al. [4] | 2004 | Interventional Lab Experiment | Pasteurization: (62.5 °C for 30 min), Freeze-thawing: (−20 °C for 18 h, 4 days and 10 days) | Germany | Mothers (preterm and term) | 6 | NA | NA | NR |
4 | Yoo et al. [28] | 2015 | Retrospective Cohort Study | Pasteurization: 62 °C for 30 min, Freeze-thawing: (−20 °C for 3 days) | Korea | Infants | 385 | <1000 | NR | NA |
5 | Stock et al. [29] | 2015 | Retrospective Cohort Study | Pasteurization: (62.5 °C for 30 min) | Austria | Infants | 323 | NR | <32 | NA |
6 | Donalisio et al. [30] | 2018 | Interventional Lab Experiment | Pasteurization: (62.5 °C for 30 min) | Italy | Mothers | 18 | NR | NR | 1 – 15 d pp |
7 | Gaya et al. [32] | 2021 | Interventional Lab Experiment | Pasteurization: (63 °C for 1, 2, 10, 30 min) | Italy | Donor | NR | NA | NA | NA |
8 | Bapistella et al. [31] | 2019 | Prospective Cohort Study | Pasteurization: (62 °C for 5 s) | Germany | Infants and Mothers (seropositive) | 87 | <1500 | <32 | NA |
9 | Buxmann et al. [35] | 2009 | Prospective Longitudinal Cohort Study | Freeze-thawing (−18 °C for various durations) | Germany | Infants | 58 | NA | <31 | NA |
10 | Wakabayashi et al. [42] | 2012 | Prospective Cohort Study | Freeze-thawing (−20 °C for various durations) | Japan | Infants | 11 | <1500 | NR | NA |
11 | Omarsdottir et al. [24] | 2015 | Prospective Longitudinal Cohort Study | Freeze-thawing (−20 °C for 3 days) | Sweden | Infants | 140 | NR | <28 | NA |
12 | Hosseini et al. [16] | 2016 | Interventional Lab Experiment | Freeze-thawing (−20 °C for 3 days) | Iran | Infants and Mothers | 25 | <2000 | <32 | NA |
13 | Balcells et al. [25] | 2016 | Prospective Observational study | Freeze-thawing (−20 °C for 3 days) | Spain | Infants | 981 | <1500 | <32 | NR |
14 | Sam et al. [17] | 2018 | Prospective Cohort Study | Freeze-thawing (−20 °C for 4 days up to 90 days) | US | Mothers | 6 | NR | NR | NR |
15 | Lloyd et al. [21] | 2016 | Interventional Lab Experiment | UV-C Irradiation (254 nm for 10 s at 1 to 5 cm) | Australia | Donor | NR | NR | NR | NR |
16 | Ben-Shoshan et al. [39] | 2016 | Interventional Lab Experiment | Microwave Irradiation (500 W and 750 W for 10 s) | Israel | Mothers | 31 | NR | NR | NR |
17 | Mikawa et al. [20] | 2019 | Interventional Lab Experiment | Microwave Irradiation (500 W for 20, 30, 40, 60 s) | Japan | None (created milk from formula) | NR | NA | NA | NA |
18 | Maschmann et al. [40] | 2019 | Interventional Lab Experiment | High Temperature Short Time (72 °C for 5 s) | Germany | Mothers | 41 | NR | NR | NA |
19 | Pitino et al. [9] | 2022 | Interventional Lab Experiment | High Pressure Processing ((350Mpa, 500 Mpa and 600 Mpa for 8 and 10 min | Canada | Donor | 1 | NR | NR | NR |
20 | Hernandez-Alverado et al. [33] | 2021 | Prospective blinded Surveillance Study | Untreated | US | Infants | 200 | <1500 | NR | NA |
21 | Jim et al. [36] | 2004 | Prospective Observational study | Untreated | Taiwan | Infants | 42 | <1500 | <35 | NA |
22 | Jim et al. [26] | 2009 | Prospective Observational Study | Untreated | Taiwan | Infants | 23 | <1500 | <35 | NA |
23 | Hayashi et al. [23] | 2011 | Prospective Longitudinal Cohort Study | Untreated | Japan | Infants | 27 | <1000 | <28 | NA |
24 | Josephson et al. [27] | 2014 | Prospective Cohort Study | Untreated | Georgia | Infants | 536 | <1700 | NR | NA |
25 | Romero Gomez et al. [38] | 2015 | Prospective Longitudinal Cohort Study | Untreated | Spain | Infants | 160 | NR | <32 | NA |
26 | Volder et al. [34] | 2021 | Prospective Cohort Study | Untreated | Denmark | Infants | 26 | NR | <32 | NA |
