Table 1 Perinatal characteristics of the non-weighted cohort.

From: Exclusive human milk diet is associated with lower risk of motor function impairment at three years of corrected age

Variables

Non-EHMD (n = 800)

EHMD (n = 258)

p valuea

Standardized mean difference

Maternal

 Age (year), median [IQR]

32 [28, 35]

33 [30, 36]

0.004

0.208

 Hypertensive disorder of pregnancy, n (%)

239 (29.9)

79 (30.6)

0.882

0.016

 Gestational diabetes mellitus, n (%)

91 (11.4)

29 (11.2)

1.000

0.004

 Obesity, n (%)

281 (35.1)

74 (28.7)

0.067

0.139

 Placental abruption, n (%)

125 (15.6)

39 (15.1)

0.922

0.014

 Chorioamnionitis, n (%)

58 (7.2)

29 (11.2)

0.058

0.138

 Antenatal corticosteroids, n (%)

750 (93.8)

250 (96.9)

0.076

0.150

 Non-smoker during pregnancy, n (%)

744 (93.0)

229 (88.8)

0.179

0.150

 Vaginal delivery, n (%)

247 (30.9)

60 (23.3)

0.023

0.172

 Fetal growth restriction, n (%)

11 (1.4)

7 (2.7)

0.243

0.095

Neonatal

 Gestational age (week), median [IQR]

30 [27,31]

27 [25,29]

<0.001

0.759

 Hispanic, n (%)

451 (56.4)

151 (58.5)

0.122b

0.252

 Male Sex, n (%)

412 (51.5)

134 (51.9)

0.960

0.009

 Birth weight (g), mean±sd

1303.1 (391.5)

963.5 (285.0)

<0.001

0.992

 Birth weight percentile, median [IQR]

54.5 [30.0, 76.8]

47.0 [17.0, 67.8]

<0.001

0.331

 Birth length percentile, median [IQR]

52.5 [31.6, 73.6]

45.9 [16.9, 73.0]

0.013

0.177

 Birth head circumference percentile, median [IQR]

52.6 [33.9, 74.8]

50.1 [25.4, 74.8]

0.061

0.134

 SGA, n (%)

77 (9.6)

49 (19.0)

<0.001

0.270

 LGA, n (%)

77 (9.6)

7 (2.7)

0.001

0.290

 1-min APGAR, median [IQR]

7 [5,8]

6 [4,7]

<0.001

0.255

 5-min APGAR, median [IQR]

8 [8, 9]

8 [7, 9]

0.006

0.199

  1. EHMD exclusive human milk diet, SGA small for gestational age, LGA large for gestational age, IQR interquartile range.
  2. aChi-squared test for categorical variables, rank-sum test for non-parametric continuous variables. Student’s t test for parametric continuous variables.
  3. bStatistical analysis was conducted to compare race/ethnicity assignments across White, Hispanic, Black, Asian, Pacific Islander, Multiple, and Other categories.