Table 2 Selected clinical outcomes to be evaluated in future clinical trials on less invasive prophylactic surfactant.
From: Prophylactic surfactant therapy in the era of less invasive surfactant delivery
Delivery room outcomes | Successful administration of prophylactic surfactant Adverse events during prophylactic surfactant administration Intubation in the delivery room |
NICU outcomes | Death during first hospitalization Intubation in the first 72 h Mechanical ventilation during the first 72 h Receipt of repeat surfactant administration Total number of surfactant doses Method of surfactant administration Need for intubation at any time Duration of mechanical ventilation Duration of non-invasive respiratory support Duration of all forms of respiratory support Duration of oxygen supplementation Receipt of post-natal corticosteroids Development of BPD BPD grade Echocardiographically-proven pulmonary hypertension Tracheostomy placement Length of stay |
Post-discharge outcomes | Oxygen therapy at home Respiratory disease in infancy Long term pulmonary function Neurodevelopment outcome |
