Abstract
Objective
Adverse Childhood Experiences (ACEs) are linked to various negative health outcomes. Although research typically focuses on ACEs during childhood and adulthood, emerging studies indicate that the effects of ACEs may affect neonates before birth. This study aimed to increase the percentage of neonates fully screened for ACEs in a Level III NICU from 2% to 50%.
Design
The project involved developing and implementing a neonatal ACEs screening tool integrated into the electronic medical record. The screening process was refined through a series of Plan-Do-Study-Act (PDSA) cycles to improve the consistency of screening.
Results
Over six months, the proportion of neonates screened for ACEs increased from 2% to 75%. Implementing a separate progress note for ACEs assessments enhanced confidentiality, with 60% of screenings documented privately.
Conclusions
This quality improvement project successfully established a standardized neonatal ACEs screening process, resulting in a higher identification rate of neonates at social risk.
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Data availability
The data for this study is not publicly available to protect the privacy of the patients involved.
References
Campbell JA, Walker RJ, Egede LE. Associations Between Adverse Childhood Experiences, High-Risk Behaviors, and Morbidity in Adulthood. Am J Prev Med. 2016;50:344–52.
Felitti VJ, Anda RF, Nordenberg D, Williamson DF, Spitz AM, Edwards V, et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study. Am J Prev Med. 1998;14:245–58.
Chapman DP, Whitfield CL, Felitti VJ, Dube SR, Edwards VJ, Anda RF. Adverse childhood experiences and the risk of depressive disorders in adulthood. J Affect Disord. 2004;82:217–25.
Chartier MJ, Walker JR, Naimark B. Separate and cumulative effects of adverse childhood experiences in predicting adult health and health care utilization. Child Abus Negl. 2010;34:454–64.
Holman DM, Ports KA, Buchanan ND, Hawkins NA, Merrick MT, Metzler M, et al. The association between adverse childhood experiences and risk of cancer in adulthood: a systematic review of the literature. Pediatrics. 2016;138:S81–91.
Malin KJ, Vittner D, Darilek U, McGlothen-Bell K, Crawford A, Koerner R, et al. Application of the Adverse Childhood Experiences Framework to the NICU. Adv Neonatal Care. :https://doi.org/10.1097/ANC.0000000000001122.
Hudziak JJ. ACEs and Pregnancy: Time to Support All Expectant Mothers. Pediatrics [Internet]. 2018 Apr [cited 2020 Jul 27];141. Available from: https://pediatrics.aappublications.org/content/141/4/e20180232
Mamun A, Biswas T, Scott J, Sly PD, McIntyre HD, Thorpe K, et al. Adverse childhood experiences, the risk of pregnancy complications and adverse pregnancy outcomes: a systematic review and meta-analysis. BMJ Open. 2023;13:e063826.
Mulder EJH, Robles de Medina PG, Huizink AC, Van den Bergh BRH, Buitelaar JK, Visser GHA. Prenatal maternal stress: effects on pregnancy and the (unborn) child. Early Hum Dev. 2002;70:3–14.
Lodha A, Lakhani J, Ediger K, Tang S, Lodha A, Gandhi V, et al. Do preterm infants with a birth weight ≤1250 g born to single-parent families have poorer neurodevelopmental outcomes at age 3 than those born to two-parent families?. J Perinatol J Calif Perinat Assoc. 2018;38:900–7.
How to Improve: Model for Improvement | Institute for Healthcare Improvement [Internet]. [cited 2025 Mar 18]. Available from: https://www.ihi.org/resources/how-improve-model-improvement
REDCap [Internet]. [cited 2023 Mar 31]. Available from: https://www.project-redcap.org/
Harris PA, Taylor R, Minor BL, Elliott V, Fernandez M, O’Neal L, et al. The REDCap consortium: Building an international community of software platform partners. J Biomed Inf. 2019;95:103208.
SQUIRE | SQUIRE 2.0 Guidelines [Internet]. [cited 2025 Oct 8]. Available from: https://www.squire-statement.org/index.cfm?fuseaction=page.viewPage&pageID=471x&nodeID=1
Higginbotham K, Davis Crutcher T, Karp SM. Screening for social determinants of health at well-child appointments: a quality improvement project. Nurs Clin North Am. 2019;54:141–8.
Friedman S, Caddle S, Motelow JE, Meyer D, Lane M. Improving screening for social determinants of health in a pediatric resident clinic: a quality improvement initiative. Pediatr Qual Saf. 2021;6:e419.
Stark AR, Pursley DM, Papile LA, Eichenwald EC, Hankins CT, Buck RK, et al. Standards for Levels of Neonatal Care: II, III, and IV. Pediatrics. 2023;151:e2023061957.
Guidelines for Perinatal Care, 8th edition [Paperback] | AAP [Internet]. [cited 2025 Mar 19]. Available from: https://www.aap.org/en/catalog/categories/neonatology-perinatal/guidelines-for-perinatal-care-8th-edition-paperback/
Funding
This study was sponsored by the University of Utah Department of Pediatrics.
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Authors and Affiliations
Contributions
Kaitlyn Sacotte designed and implemented the study and wrote the manuscript. Carrie Torr helped design the study and edited the manuscript. Jane Nampijja implemented the study and helped edit the manuscript.
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Competing interests
The authors of this manuscript have no competing financial interests in relation to this work.
Ethics approval and consent to participate
This study was approved by the Institutional Review Board at the University of Utah (Study Number 00158943) and received ethics approval. All methods were performed in accordance with the relevant guidelines and regulations. Informed consent was waived by the Institutional Review Board due to minimal risk of harm.
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Sacotte, K., Nampijja, J. & Torr, C. Improving Neonatal Adverse Childhood Experiences (ACEs) Screening in the NICU: A Quality Improvement Initiative. J Perinatol (2025). https://doi.org/10.1038/s41372-025-02498-5
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DOI: https://doi.org/10.1038/s41372-025-02498-5


