Fig. 5 | Laboratory Investigation

Fig. 5

From: Maresin 1 attenuates mitochondrial dysfunction through the ALX/cAMP/ROS pathway in the cecal ligation and puncture mouse model and sepsis patients

Fig. 5

The Effect of MaR1 on bacterial clearance and leukocytes diversification was dependent on MaR1 receptor (ALX) in CLP model. MaR1 (100ng/mice, i.p.) and BOC-2 (600 ng/kg, i.p.) were co-administered to CLP mice, and peritoneal lavage fluid samples were collected 24 h after operation and the CFU (a) and immune cells (b, c, d) was calculated. Data are presented as mean ± SEM. n = 8–12. P5: Macrophages. P6: Neutrophils. *p < 0.05 vs. CLP group. #p < 0.05, ##p < 0.01 vs. CLP+MaR1 group

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