Fig. 7 | Laboratory Investigation

Fig. 7

From: Maresin 1 attenuates mitochondrial dysfunction through the ALX/cAMP/ROS pathway in the cecal ligation and puncture mouse model and sepsis patients

Fig. 7

MaR1 downregulated ROS production via regulating the enzyme NOX, SOD and CAT activity in CLP mice. MaR1 (100ng/mice) with or without BOC-2 (600 ng/kg) or SQ22536 (10 mg/kg) was co-administrated to CLP mice, lung tissues were collected 24 h after CLP, then ROS production(a), NOX(b), SOD(c) and CAT(d) activity in the lung tissue was detected. Data are presented as mean ± SEM. n = 6–8. *p < 0.05,**p < 0.01 vs. CLP group. #p < 0.05, ##p < 0.01 vs. CLP+MaR1 treatment group

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