Table 1 Non-fasting glucose levels in non-diabetic and diabetic mice

From: SOCS1-targeted therapy ameliorates renal and vascular oxidative stress in diabetes via STAT1 and PI3K inhibition

Days post-STZ

Non-diabetes

(n = 6)

Diabetes (early intervention)

Diabetes (late intervention)

Control

(n = 6)

Ad-null

(n = 8)

Ad-S1

(n = 8)

Vehicle

(n = 6)

miS1

(n = 6)

Vehicle

(n = 10)

Mut

(n = 7)

miS1

(n = 10)

0

7.1 ± 0.4

7.2 ± 0.4

5.1 ± 0.6

7.3 ± 0.6

6.5 ± 0.6

6.3 ± 0.7

6.9 ± 0.9

6.2 ± 0.4

6.4 ± 0.6

10

6.8 ± 0.9

25.4 ± 2.7*

22.8 ± 2.0*

23.0 ± 1.4*

22.4 ± 1.9*

22.8 ± 2.0*

23.2 ± 3.7*

21.6 ± 2.0*

22.1 ± 3.9*

21

7.1 ± 1.0

27.6 ± 0.8*

26.5 ± 1.4*

29.8 ± 2.1*

23.1 ± 2.7*

26.4 ± 3.1*

23.1 ± 2.8*

22.9 ± 2.8*

26.1 ± 0.7*

41

8.5 ± 1.1

28.3 ± 1.0*

29.6 ± 0.8*

31.5 ± 1.1*

26.8 ± 2.3*

26.0 ± 1.2*

27.2 ± 2.7*

29.9 ± 2.2*

28.7 ± 2.1*

63

8.0 ± 0.7

–-

–

–

–

–

28.3 ± 1.7*

26.4 ± 2.7*

26.4 ± 4.1*

83

6.5 ± 0.2

–

–

–

–

–

30.1 ± 2.2*

31.3 ± 1.7*

28.8 ± 1.8*

  1. Blood glucose values are expressed as mmol/L
  2. *P  <0.05 vs day 0
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