Fig. 2 | Laboratory Investigation

Fig. 2

From: Nanovesicle-mediated delivery of anticancer agents effectively induced cell death and regressed intrahepatic tumors in athymic mice

Fig. 2

Characterization of doxorubicin-loaded MNV (dox-MNV). a Dox-MNV after ultracentrifugation. The supernatant was very clear without a trace of doxorubicin after second wash. b Size/concentration analysis of dox-MNV using NanoSight. c UV–visible spectrum of pure doxorubicin and dox-MNV at a fixed concentration of 50 μg/ml. d Concentration curve fitting of dox-MNV ranging from 10 to 50 μg/ml at 490 nm. eZeta potential measurements of plain MNV and after internalization of doxorubicin and anti-miR221. e1 Plain MNV and e2 dox-MNV. e3 Anti-miR221 loaded MNV. e4 Quantitative analysis of zeta potential measurements. Data are mean ± SD of five samples in each group

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