Fig. 1 | Laboratory Investigation

Fig. 1

From: BMP-2 restoration aids in recovery from liver fibrosis by attenuating TGF-β1 signaling

Fig. 1

Downregulation of BMP-2 in human hepatitis and cirrhotic livers. a Immunohistochemistry (IHC) analysis of BMP-2 and TGF-β1 expression in human fibrotic liver tissue microarray (TMA). TMA slides containing normal, hepatitis, and cirrhosis livers were subjected to IHC staining with BMP-2 and TGF-β1. Arrows indicate hepatocytes; arrowheads indicate HSCs. b, c Quantification of BMP-2 and TGF-β1 expression levels from IHC staining results. Data represent the mean ± SEM. *P < 0.05 compared between the indicated groups

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