Fig. 2
From: High-mobility group box 1 induces endoplasmic reticulum stress and activates hepatic stellate cells
HMGB1 induces the activation, proliferation and migration of HSCs. a Western blot analysis of α-SMA and collagen-1 in LX-2, R-HSC and HSC-T6 cells treated with various doses of rhHMGB1 for 24 h. b The proliferation rates of LX-2, R-HSC and HSC-T6 cells treated with various dose of rhHMGB1 were determined by CCK-8 assay. c The migration of LX-2, R-HSC and HSC-T6 cells treated with rhHMGB1 was analyzed by transwell assay. d Representative images of the wound-healing assay with LX-2 and HSC-T6 cells treated with various doses of rhHMGB1 for 24 h. *P<0.05, **P<0.01, ***P<0.001.
