Fig. 1 | Laboratory Investigation

Fig. 1

From: Interferon-γ mediates the protective effects of soluble receptor for advanced glycation end-product in myocardial ischemia/reperfusion

Fig. 1

sRAGE increased expression of IFN-γ in MI/R mice. a Levels of IFN-γ in the serum of mice with or without sRAGE in sham- and MI/R-treated mice. b IFN-γ mRNA levels in hearts of sham- and MI/R-treated mice with or without sRAGE. c Representative immunohistochemistry staining of IFN-γ in hearts of sham- and MI/R-treated mice with or without sRAGE treatment (magnification: × 20). Scale bar: 50 μm. d Representative quantification of IFN-γ-positive cells in heart tissue with or without sRAGE treatment during MI/R. Scale bar: 20 μm. Values are expressed as the mean ± SEM (n = 6 mice per group) *p < 0.05; **p < 0.01; ***p < 0.001

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