Fig. 3 | Laboratory Investigation

Fig. 3

From: Interferon-γ mediates the protective effects of soluble receptor for advanced glycation end-product in myocardial ischemia/reperfusion

Fig. 3

Neutralization of IFN-γ abolished the upregulating effect of sRAGE on proteasome subunits in MI/R-treated hearts. a Representative images of western blot for β1i, β2i and β5i in mouse hearts with or without sRAGE and anti-IFN-antibody treatment. b Quantification of the relative expression of β1i in mouse hearts. c Quantification of relative expression of β2i in mouse hearts. d Quantification of the relative expression of β5i in mice hearts. e Quantification of the relative caspase-like, trypsin-like and chymotrypsin-like activities in mouse hearts with or without sRAGE and anti-IFN-antibody treatment. Values are expressed as the mean ± SEM (n = 6 mice per group). *p < 0.05; **p < 0.01

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