Fig. 5
From: The direct binding of collagen XVII and collagen IV is disrupted by pemphigoid autoantibodies
mAbs targeting the C-terminus of COL17 reduce the cell attachment strength by disrupting the binding of COL17 to COL4 in NHOMKs. a The remaining cell number in the culture plates with or without COL4 coating after vibration stress. b The remaining cell number in COL4-coated plates with the stimulation with mAb C17-C1 or mIgG1 after vibration stress. c The relative COL17 amounts were evaluated after the 12-h stimulation with mAbs C17-C1, TS39-3, or mIgG1. The data are expressed as the means ± S.D. One-way ANOVA. **0.001 < p < 0.01, ***0.0001 < p < 0.001
