Table 2 Association between human GEO deposits’ technology used (high-throughput sequencing technology vs. other methods) and their corresponding geographic origin (North America vs. other regions) from 2008 to 2017

From: Trends in the characteristics of human functional genomic data on the gene expression omnibus, 2001–2017

 

North America

Other regions

   

Year

HTS

Other method

HTS

Other method

OR

95% CI

P value

2008

18

623

3

525

5.06

1.48–17.26

3.59E−03

2009

40

820

9

730

3.96

1.91–8.21

5.70E−05

2010

106

920

46

954

2.39

1.67–3.42

8.07E−07

2011

165

1201

100

1182

1.62

1.25–2.11

2.74E−04

2012

240

1192

173

1483

1.73

1.40–2.13

3.27E−07

2013

360

1310

233

1611

1.90

1.59–2.28

2.16E−12

2014

549

1209

413

1830

2.01

1.74–2.33

7.93E−21

2015

726

1319

488

2017

2.27

1.99–2.60

7.31E−34

2016

2436

1150

684

1877

5.81

5.20–6.50

1.31E−229

2017

3643

1313

983

1955

5.52

5.00–6.09

6.33E−270

Total

8283 (22.6%)

11,057 (30.2%)

3132 (8.5%)

14,164 (38.7%)

3.39

3.23–3.55

9.40E−323

  1. Note: Odds ratio (OR) represents the odds that a GEO deposit using HTS originated from North America. No deposits using HTS were identified in the GEO prior to 2008. HTS high-throughput sequencing; CI confidence intervals