Fig. 1 | Laboratory Investigation

Fig. 1

From: Vitamin D protects human melanocytes against oxidative damage by activation of Wnt/β-catenin signaling

Fig. 1

Serum vitamin D insufficiency or decreased VDR expression was associated with vitiligo pathogenesis. a Decreased serum vitamin D levels and (b) increased serum MDA levels in patients with vitiligo. Ctrl healthy controls, PV progressive vitiligo, SV stable vitiligo, Total total patients. c Association between serum vitamin D and MDA levels. Serum vitamin D levels were inversely correlated with serum MDA levels in vitiligo patients (r = −0.3185, p = 0.0201, n = 53, Spearman’s correlation test). The solid line represents the regression line. d Vitiligo melanocytes showed lower expression of vitamin D receptor (VDR) than normal melanocytes. *P < 0.05, **P < 0.01, ***P < 0.001

Back to article page